Hello smeier,
I don’t know, i’ve tried to do this for my own enterprise storage requirements, i work in an company, and i’m the senior sysadmin. I’m trying to move from OS based storage, to i SCSI disks on bare metal servers, and to serve the iSCSI virtual disk to the Virtual OS that will hold the OS for the samba server, thus having the OS and the data separated, from my point of view it’s more simpler and easier, because in case of some OS problems, or i want to make backups, it’s simpler like this, i just connect another iSCSI disk and i can migrate all the data to that disk .
Cheers,
Andrei